Ozempic: Facts and Fiction - Atriummednyc

Ozempic: Facts and Fiction

Ozempic: Facts and Fiction

As a cutting-edge primary care practice in New York City, we are committed to providing our patients with the latest and most accurate medical information. Here’s some facts about Ozempic and Wegovy to get you started! Ask your Atrium provider about these medications at your next visit if you’re interested.

What's the difference between Ozempic and Wegovy?

Ozempic and Wegovy are two brand names for the same medication, semaglutide. Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which is a type of medication that works by mimicking the effects of the GLP-1 hormone. GLP-1 is a naturally occurring hormone that helps to regulate blood sugar levels and appetite.

What conditions are Ozempic and Wegovy used to treat?

Ozempic is approved by the US Food and Drug Administration (FDA) for the treatment of type 2 diabetes and for reducing the risk of major cardiovascular events in adults with type 2 diabetes and high blood sugar levels. Wegovy is approved by the FDA for the treatment of chronic weight management in adults with obesity or overweight and at least one weight-related medical condition, such as high blood pressure, type 2 diabetes, or high cholesterol.

Who is a good candidate for Ozempic or Wegovy?

Ozempic and Wegovy are generally considered to be safe and effective medications for most people. However, they are not appropriate for everyone. People with the following conditions should not take Ozempic or Wegovy:

A history of medullary thyroid cancer
Multiple endocrine neoplasia type 2
A personal or family history of pancreatitis
Hypersensitivity to semaglutide or any of the other ingredients in Ozempic or Wegovy

Ozempic and Wegovy should also be used with caution in people with the following conditions:

Kidney disease
Liver disease
Diabetic retinopathy
Inflammatory bowel disease
Eating disorders

What are the side effects of Ozempic and Wegovy?

The most common side effects of Ozempic and Wegovy are mild and go away on their own within a few weeks or months. These side effects may include:

Abdominal pain

Less common but more serious side effects of Ozempic and Wegovy can include:

Allergic reactions
Low blood sugar
Gallbladder problems
Thyroid problems
Increased risk of depression

How are Ozempic and Wegovy administered?

Ozempic and Wegovy are both injectable medications that are given once a week under the skin. The starting dose for Ozempic is 0.25 milligrams (mg) once a week. The starting dose for Wegovy is 0.25 mg once a week. The dose can be gradually increased over time, based on the individual’s response to the medication.

How effective are Ozempic and Wegovy?

Ozempic and Wegovy have been shown to be very effective in both lowering blood sugar levels and promoting weight loss. In clinical trials, Ozempic reduced blood sugar levels by an average of 1.5% to 2% and reduced weight by an average of 5% to 10%. Wegovy reduced blood sugar levels by an average of 1.8% to 2.4% and reduced weight by an average of 15% to 20%.


Ozempic and Wegovy are two new and innovative medications that can be very effective in treating type 2 diabetes and promoting weight loss. If you are interested in learning more about whether Ozempic or Wegovy is right for you, please talk to your Atrium provider.

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